Daniil Medvedev became the highest seed to fall in the French Open singles after losing to Australia’s Alex de Minaur in the men’s fourth round.
Russian fifth seed Medvedev was beaten 4-6, 6-2, 6-1, 6-3 at Roland Garros.
Medvedev needed treatment for blisters on his feet in the second set and lost nine of the next 10 games when he returned from a medical timeout.
The former world number one, who has never gone past the French Open quarter-finals, improved in the fourth set after going off court again.
De Minaur will play either German fourth seed Alexander Zverev or Danish 13th seed Holger Rune in the quarter-finals.
On the women’s side, Aryna Sabalenka sent an ominous message to her rivals as she powered past Emma Navarro to reach the quarter-finals.
Australian Open champion Sabalenka played with controlled aggression to complete a dominant 6-2, 6-3 win over 22nd seed Navarro.
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